Figure 8 | Scientific Reports

Figure 8

From: Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells

Figure 8

Alternative spliced variants of CHOP. (A) A computational analysis detecting CHOP differential alternative splicing events obtained from the microarray study of SW480 treated with and without ONC201. (B) Bioanalyzer electrophoresis after quantitative PCR analysis of LS-174T and SW480 cells treated with and without ONC201. CHOP was amplified using specific primers flanking the exons 1 and 4. PCR products were fractionated on Bioanalyzer microgel. Alternative spliced isoforms were mapped according to their fragment size.

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