Table 2 Univariate and multivariate analyses of relapse-free survival.

From: Comprehensive profiling of novel epithelial–mesenchymal transition mediators and their clinical significance in colorectal cancer

Variable

Univariate

Multivariate

HR

95% CI

p value

HR

95% CI

p value

Sex (male/female)

1.237

0.405–3.782

0.709

   

Preoperative CEA (≥ 5/< 5)

5.810

1.748–19.31

0.004

2.484

0.662–9.314

0.177

Primary tumor site (rectum/colon)

0.746

0.205–2.713

0.657

   

Tumor invasion (T3–4/Tis, T1–2)

2.510

0.691–9.124

0.162

   

Lymph node metastasis (present/absent)

5.114

1.573–16.63

0.007

1.358

0.322–5.718

0.677

Lymphatic invasion (present/absent)

4.336

0.961–19.57

0.056

   

Venous invasion (present/absent)

6.854

2.109–22.28

0.001

4.251

1.114–16.22

0.034

ARC expression (positive/negative)

4.677

1.528–14.31

0.007

5.306

1.366–20.61

0.016

  1. HR hazard ratio, CI confidence interval, CEA carcinoembryonic antigen.
  2. HR and 95%CI of histological grade cannot be calculated because none of the five patients with Por or Muc had cancer relapse.
  3. Bold values indicate p < 0.05.
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