Table 3 Attributable risk of common hATTR amyloidosis manifestations in the UK Biobank African ancestry population (n = 6062) due to the V122I variant.
Diagnoses in V122I carriers (%) (n/N) | Population attributable risk to V122I variant (%) | |
---|---|---|
Polyneuropathy | 20.0 (5/25) | 16.7 |
CTS | 7.5 (13/174) | 4.1 |
Cardiomyopathy | 7.5 (3/40) | 2.4 |
HF | 10.2 (10/98) | 6.5 |
At least one common hATTR amyloidosis manifestation | 8.7 (27/311) | 5.5 |