Table 2 Pearson correlation analyses of eGFR at baseline with selected variables at follow-up.

From: Estimated glomerular filtration rate and cardiometabolic risk factors in a longitudinal cohort of children

Baseline eGFR

All (N = 401)

Normal weight (N = 283)

Overweight (N = 118)

Follow-up

r

p value

r

p value

r

p value

Age (years)

0.334

< 0.0001

0.239

< 0.0001

0.450

< 0.0001

BMI-SDS

0.120

0.01

− 0.013

NS

0.215

0.02

Height-SDS

0.006

NS

− 0.048

NS

0.010

NS

Weight-SDS

0.112

0.02

− 0.035

NS

0.224

0.01

Waist (cm)

0.151

0.003

0.010

NS

0.341

< 0.0001

SBP (mmHg)

0.315

< 0.0001

0.249

< 0.0001

0.420

< 0.0001

DBP (mmHg)

0.219

< 0.0001

0.221

< 0.0001

0.141

NS

Glucose (mg/dL)

− 0.084

NS

− 0.100

NS

− 0.056

NS

Creatinine (mg/dl)

− 0.205

< 0.0001

− 0.314

< 0.0001

− 0.123

NS

Insulin (µU/mL)

0.354

< 0.0001

0.341

< 0.0001

0.346

< 0.0001

HOMA-IR

0.341

< 0.0001

0.324

< 0.0001

0.327

< 0.0001

HDL-cholesterol (mg/dL)

0.056

NS

0.135

0.02

− 0.032

NS

LDL-cholesterol (mg/dL)

0.091

NS

0.075

NS

0.138

NS

Total cholesterol (mg/dL)

− 0.110

0.024

− 0.119

0.04

− 0.026

NS

Triacylglycerol (mg/dL)

0.067

NS

0.024

NS

0.037

NS

Renal length (cm)

0.317

< 0.0001

0.205

0.001

0.463

< 0.0001

Renal volume (cm3)

0.372

<0.0001

0.259

<0.0001

0.536

<0.0001

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, HOMA-IR homeostatic model assessment of insulin resistance, NS non-significant.
  2. Moderate associations (Pearson’s r > 0.3) are shown in bold.