Figure 4
From: Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH

Microarray analysis of cellular pathways with gene dysregulation. CVD compared to HFD: (A) pathways with upregulated genes and (B) cellular tracks with decreased gene expression. PFD compared to HFD: (C) shows cell processes with gene overexpression and (D) metabolic pathways with decreased gene expression. CVD conventional diet, HFD high fat and high carbohydrate diet, PFD high fat and high carbohydrate diet + prolonged-release pirfenidone.