Table 2 Characteristics of subjects in the top quartile vs bottom quartiles of 11-gene scores.

From: Prospective validation of an 11-gene mRNA host response score for mortality risk stratification in the intensive care unit

 

Bottom quartiles* (n = 55)

Top quartile* (n = 15)

P-value

Median age (IQR)

71 (61–80)

67 (61–81)

0.88

% Female

38%

47%

0.57

Race

White

39 (71%)

13 (87%)

0.32

Black/African American

4 (7%)

0 (0%)

0.57

Asian/Pacific Islander

5 (9%)

2 (13%)

0.64

Other/unknown

7 (13%)

0 (0%)

0.33

Infection

36 (65%)

11 (73%)

0.73

Median SAPS 3 (IQR)

59 (51–73)

64 (59–79)

0.14

Median APACHE II (IQR)

20 (17–25)

26 (21–31)

0.02

Shock

22 (40%)

11 (73%)

0.04

Primary determinant of prognosis

MODS and/or ARDS

16 (29%)

6 (40%)

0.53

Mixed

20 (36%)

6 (40%)

1

Comorbidities

19 (35%)

3 (20%)

0.36

60-day mortality

8 (15%)

6 (40%)

0.06

  1. *Top quartile cutoff was calculated based on all 11-gene scores (all 165 patients).