Table 4 Association between sleep before pregnancy and infant development, Japan Environment and Children's Study (2011–2014).

From: Association of maternal sleep before and during pregnancy with sleep and developmental problems in 1-year-old infants

 

No. of participants

No. of outcome

Maternal age adjusted model

Multivariable modela

 

%

RR

95% CI

RR

95% CI

Communication

Sleep duration

 < 6 h

4489

5

0.1

1.19

0.45

3.15

1.15

0.43

3.03

 6 < 7

13,427

18

0.1

1.40

0.75

2.61

1.32

0.71

2.47

 7 < 8

23,058

22

0.1

Ref

  

Ref

  

 8 < 9

16,779

13

0.1

0.82

0.41

1.63

0.90

0.45

1.80

 9 < 10

6863

6

0.1

0.95

0.39

2.35

1.12

0.45

2.82

 10<

2975

3

0.1

1.29

0.38

4.31

1.42

0.42

4.78

Bedtime

 21 < 24

45,971

46

0.1

Ref

  

Ref

  

 24 < 27

19,816

19

0.1

1.01

0.59

1.73

0.86

0.49

1.50

 Other

1804

2

0.1

1.33

0.32

5.51

1.39

0.33

5.79

Gross motor skills

Sleep duration

 < 6 h

4489

265

5.9

1.08

0.95

1.23

1.07

0.94

1.22

 6 < 7

13,427

832

6.2

1.12

1.03

1.22

1.11

1.02

1.20

 7 < 8

23,066

1264

5.5

Ref

  

Ref

  

 8 < 9

16,775

902

5.4

0.99

0.91

1.07

1.02

0.93

1.10

 9 < 10

6861

327

4.8

0.89

0.79

1.01

0.94

0.84

1.06

 10<

2975

120

4.0

0.82

0.69

0.99

0.86

0.72

1.03

Bedtime

 21 < 24

45,972

2546

5.5

Ref

  

Ref

  

 24 < 27

19,816

1073

5.4

1.01

0.95

1.09

0.97

0.90

1.05

 Other

1805

91

5.0

1.01

0.83

1.24

1.06

0.86

1.30

Fine motor skills

Sleep duration

 < 6 h

4489

252

5.6

1.01

0.88

1.15

1.02

0.90

1.17

 6 < 7

13,415

781

5.8

1.04

0.95

1.13

1.05

0.97

1.15

 7 < 8

23,063

1283

5.6

Ref

  

Ref

  

 8 < 9

16,766

932

5.6

1.01

0.93

1.09

0.99

0.91

1.08

 9 < 10

6859

373

5.4

1.00

0.90

1.12

0.98

0.87

1.09

 10<

2974

141

4.7

0.95

0.80

1.12

0.93

0.79

1.10

Bedtime

 21 < 24

45,951

2623

5.7

Ref

  

Ref

  

 24 < 27

19,811

1053

5.3

0.96

0.90

1.03

1.00

0.93

1.07

 Other

1804

86

4.8

0.92

0.74

1.13

0.94

0.76

1.16

Problems solving

Sleep duration

 < 6 h

4482

246

5.5

1.09

0.95

1.25

1.06

0.93

1.21

 6 < 7

13,404

726

5.4

1.08

0.98

1.18

1.04

0.95

1.14

 7 < 8

23,041

1151

5.0

Ref

  

Ref

  

 8 < 9

16,757

831

5.0

1.00

0.92

1.09

1.05

0.96

1.15

 9 < 10

6848

343

5.0

1.03

0.91

1.16

1.12

1.00

1.26

 10 < 

2973

141

4.7

1.04

0.88

1.24

1.10

0.93

1.31

Bedtime

 21 < 24

45,918

2321

5.1

Ref

  

Ref

  

 24 < 27

19,785

1042

5.3

1.08

1.00

1.16

1.00

0.93

1.08

 Other

1802

75

4.2

0.89

0.71

1.12

0.90

0.72

1.13

Personal-social characteristics

Sleep duration

 < 6 h

4480

50

1.1

1.11

0.82

1.51

1.20

0.88

1.62

 6 < 7

13,402

142

1.1

1.05

0.85

1.29

1.12

0.91

1.37

 7 < 8

23,017

231

1.0

Ref

  

Ref

  

 8 < 9

16,731

222

1.3

1.33

1.11

1.60

1.23

1.02

1.48

 9 < 10

6852

99

1.4

1.48

1.17

1.87

1.30

1.03

1.65

 10<

2971

34

1.1

1.27

0.89

1.82

1.18

0.82

1.69

Bedtime

 21 < 24

45,874

554

1.2

Ref

  

Ref

  

 24 < 27

19,778

211

1.1

0.91

0.78

1.07

1.10

0.93

1.29

 Other

1801

13

0.7

0.66

0.38

1.14

0.72

0.41

1.24

Total (abnormal score for any 1 of the 5 domain)

Sleep duration

 < 6 h

4491

621

13.8

1.01

0.94

1.10

1.01

0.93

1.09

 6 < 7

13,432

1917

14.3

1.04

0.99

1.10

1.03

0.98

1.08

 7 < 8

23,070

3146

13.6

Ref

  

Ref

  

 8 < 9

16,783

2218

13.2

0.98

0.93

1.03

0.99

0.95

1.05

 9 < 10

6865

874

12.7

0.96

0.89

1.03

0.99

0.92

1.06

 10<

2976

365

12.3

1.00

0.90

1.10

1.02

0.92

1.13

Bedtime

 21 < 24

45,987

6285

13.7

Ref

  

Ref

  

 24 < 27

19,823

2645

13.3

1.01

0.97

1.05

0.98

0.94

1.03

 Other

1807

211

11.7

0.94

0.82

1.07

0.97

0.85

1.10

  1. CI confidence interval, RR risk ratio. Bold fonts showed the items of the Ages and Stages Questionnaire. 
  2. aAdjusted for maternal age at delivery, smoking habits, alcohol consumption, pre-pregnancy body mass index, gestational age at birth, parity, infertility treatment, and infant sex.