Table 1 Repeatability (intra-assay precision) and reproducibility (inter-assay precision).
High PC | Middle PC | Low PC | Negative cut-off | |||
|---|---|---|---|---|---|---|
Intra-assay | Rat | Mean (%CV) | 3.337 (2.6%) | 1.512 (3.4%) | 0.150 (4.3%) | 0.067 (6.3%) |
Monkey | Mean (%CV) | 3.204 (1.8%) | 1.367 (2.0%) | 0.178 (8.3%) | 0.083 (9.7%) | |
Inter-assay | Rat | Mean (%CV) | 3.414 (1.6%) | 1.618 (5.4%) | 0.169 (6.7%) | 0.068 (4.6%) |
Ratio (%CV)a | 49.9 (5.1%) | 23.7 (5.8%) | 2.5 (6.2%) | − | ||
Monkey | Mean (%CV) | 3.255 (2.3%) | 1.469 (8.6%) | 0.183 (10.6%) | 0.086 (4.0%) | |
Ratio (%CV) | 37.9 (3.9%) | 17.1 (9.4%) | 2.1 (11.7%) | − | ||
Stability (freeze/thaw) | Rat | Mean | 3.306 | NAc | 0.179 | 0.072 |
Ratio (%difference)b | 45.9 (8.0%) | NA | 2.5 (0%) | − | ||
Monkey | Mean | 3.287 | NA | 0.185 | 0.088 | |
Ratio (%difference) | 37.4 (1.3%) | NA | 2.1 (0%) | − | ||
Stability (12-week) | Rat | Mean | 3.431 | NA | 0.208 | 0.069 |
Ratio (%difference) | 49.7 (0.4%) | NA | 3.0 (20%) | − | ||
Monkey | Mean | 3.360 | NA | 0.206 | 0.084 | |
Ratio (%difference) | 40 (5.5%) | NA | 2.5 (19%) | − | ||
