Table 3 Experimental design of the current toxicity study of GX-G3 treatment in rats and monkeys.
Species | Group | Dose (mg/kg) | Number of animals (male/female) | |
|---|---|---|---|---|
Week 0, 2, and 4 | Week 8 | |||
(Dosing day 1a, 14, and day 28) | (Recovery day 29) | |||
Rats | Vehicle control | 0 | 3/3 | 3/3 |
T1 | 1 | 3/3 | 3/3 | |
T2 | 3 | 3/3 | 3/3 | |
T3 | 10 | 3/3 | 3/3 | |
Species | Group | Dose (mg/kg) | Week 0, 1, 3, and 4 | Week 8 |
|---|---|---|---|---|
(Dosing day 1, 8, 22, and 29) | (Recovery day 30) | |||
Monkeys | Vehicle control | 0 | 3/3 | 2/2 |
T1 | 1 | 3/3 | – | |
T2 | 3 | 3/3 | – | |
T3 | 10 | 3/3 | 2/2 |
