Figure 3

Combination treatment with rt-PA + U0126 prevents the increased MMP-9 expression after delayed rt-PA treatment. (a) Representative western blots and scatter plots displaying expression of MMP-9.MMP-9 expression levels were normalized to control. (b) Representative zymography blots and scatter plots illustrate MMP-9 protein expression. The expression levels were normalized to control group which was set to 100%. All data are presented as median ± IQR, *P < 0.05 is considered statistically significant, n = 3–7.