Figure 1

Synthesis of a computational brain model using the graph approach. White matter connections can be extracted by means of DTI. Brains of individual subjects can be coregistered to a parcellation template (atlas) in order to assign connections to couples of brain areas. After conferring local dynamics to the nodes of the structural connectome obtained, the network activity emerges from the interaction of the component nodes. The number of nodes of the model depends on the template used, and each node can be represented at different levels of abstraction (e.g., ensemble of spiking neurons).