Table 1 Changes in gene expression in Rev-erbα KO MEFs relative to WT by a glycolysis gene array.
Genes | Fold change | Full name of genes |
|---|---|---|
Aldob | − 3.50 | Aldolase B, fructose-bisphosphate |
Aldoc | 2.11 | Aldolase C, fructose-bisphosphate |
Cs | 1.67 | Citrate synthase |
Dlat | 1.5 | Dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) |
Dlst | − 8.54 | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
Eno1 | − 7.20 | Enolase 1, alpha non-neuron |
Eno2 | − 1.66 | Enolase 2, gamma neuronal |
Fbp1 | − 1.31 | Fructose bisphosphatase 1 |
G6pc3 | − 5.12 | Glucose 6 phosphatase, catalytic, 3 |
G6pdx | − 1.36 | Glucose-6-phosphate dehydrogenase X-linked |
Galm | − 1.19 | Galactose mutarotase |
Gpi1 | 1.39 | Glucose phosphate isomerase 1 |
Gys1 | − 1.76 | Glycogen synthase 1, muscle |
Gys2 | − 1.62 | Glycogen synthase 2 |
Hk2 | − 1.76 | Hexokinase 2 |
Hk3 | − 1.72 | Hexokinase 3 |
Idh3a | 1.02 | Isocitrate dehydrogenase 3 (NAD +) alpha |
Idh3b | − 2.00 | Isocitrate dehydrogenase 3 (NAD +) beta |
Idh3g | − 1.36 | Isocitrate dehydrogenase 3 (NAD +), gamma |
Mdh1 | 1.1 | Malate dehydrogenase 1, NAD (soluble) |
Ogdh | 1.75 | Oxoglutarate dehydrogenase (lipoamide) |
Pcx | 1.25 | Pyruvate carboxylase |
Pdha1 | − 1.9 | Pyruvate dehydrogenase E1 alpha 1 |
Pdhb | 4.82 | Pyruvate dehydrogenase (lipoamide) beta |
Pdk1 | 1.79 | Pyruvate dehydrogenase kinase, isoenzyme 1 |
Pdk2 | − 16.05 | Pyruvate dehydrogenase kinase, isoenzyme 2 |
Pdk3 | − 1.77 | Pyruvate dehydrogenase kinase, isoenzyme 3 |
Pdp2 | − 1.12 | Pyruvate dehyrogenase phosphatase catalytic subunit 2 |
Pgam2 | − 2.66 | Phosphoglycerate mutase 2 |
Pgk2 | − 4.51 | Phosphoglycerate kinase 2 |
Phkb | − 3.58 | Phosphorylase kinase beta |
Phkg1 | − 2.15 | Phosphorylase kinase gamma 1 |
Prps1 | 1.55 | Phosphoribosyl pyrophosphate synthetase 1 |
Prps1l1 | − 1.36 | Phosphoribosyl pyrophosphate synthetase 1-like 1 |
Prps2 | 1.61 | Phosphoribosyl pyrophosphate synthetase 2 |
Pygl | 170.28 | Liver glycogen phosphorylase |
Pygm | − 2.18 | Muscle glycogen phosphorylase |
Rbks | 1.78 | Ribokinase |
Rpe | − 1.9 | Ribulose-5-phosphate-3-epimerase |
Rpia | 1.96 | Ribose 5-phosphate isomerase A |
Sdhb | 1.39 | Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
Sucla2 | 1.00 | Succinate-Coenzyme A ligase, ADP-forming, beta subunit |
Suclg2 | − 2.11 | Succinate-Coenzyme A ligase, GDP-forming, beta subunit |
Taldo1 | − 1.79 | Transaldolase 1 |
Tkt | 2.04 | Transketolase |
