Figure 1

Overview of the experimental approach. Five-week-old C57BL/6 N male mice were orally administered different doses (0.5 g, 1.0 g, and 2.0 g/kg) of Korean red ginseng (KRG). After 4 weeks, serum and liver tissue were extracted for serum chemistry and proteomic analysis (A). Glucose levels and AST and ALT levels in the serum (B). Histological analysis of H & E staining of liver tissue at 200 × magnification. White arrows indicate inflammatory cell infiltration. Scale bar represents 150 mm. (C). Results are shown as the mean ± SEM of five to six animals per group. Statistical significance was set at * p < 0.05 and ** p < 0.01 compared with the control based on an ANOVA (SPSS Statistics 23 software package, https://www.ibm.com/analytics/spss-statistics-software).