Table 1 Specifications for a minimally acceptable ventilator to treat COVID-19 patients with mild or moderate symptoms.

From: Repurposing CPAP machines as stripped-down ventilators

Ventilation variable

Description

Values

Triggering mechanism

A method to initiate the inspiration phase

Time-triggering, flow-triggering

Cycling mechanism

A method to end the inspiration phase

Time-cycling, flow-cycling

Breath control variable

A parameter that describes the mechanism to assist the patient’s breathing

Pressure-control (PC)

Breath sequence

A pattern of mandatory and/or spontaneous breaths

Intermittent mandatory ventilation (IMV)

Targeting Scheme

A method used by the ventilator to achieve a specific ventilation pattern

Set-point (s)

Ventilation Mode

A term to describe the set of ventilation operations based on the selected breath control variable, breath sequence and targeting scheme

PC-IMVs,s

I:E ratio

The ratio of the inspiration (I) and the expiration (E) phase during ventilation

1:1, 1:2

Respiratory rate

The number of breaths per minute (bpm). Here, it is the number of mandatory breaths per minute. The number of spontaneous breaths per minute cannot be lower than the number of mandatory breaths per minute

8–30 bpm

Positive end-expiratory pressure (PEEP)

The airway pressure at the end of the exhalation phase

At least 5 cmH2O

Peak inspiratory pressure

The airway pressure set at the CPAP machine

15–20 cmH2O

Maximum airway pressure

The upper-pressure limit in the patient’s airways

30 cmH2O