Figure 2 | Scientific Reports

Figure 2

From: hsp-90 and unc-45 depletion induce characteristic transcriptional signatures in coexpression cliques of C. elegans

Figure 2

unc-45 RNAi leads to delayed conclusion of sperm and vulva development. (a) Average gene expression difference of the experiments, determined with TAC, compared to the control RNAi. (b) Clique map for experiment 1 of unc-45 RNAi versus young adult of control RNAi. A more detailed description of the most strongly affected cliques can be found in Table 3 and corresponds to the positions in the clique map. (c) Comparison between experiment 1 and 2 on a gene-by-gene basis (upper panel) and comparison between experiment 1 and 2 on a clique-by-clique basis (lower panel). The clique map of experiment 2 is shown as Supplemental Fig. 2b, d) Clique trends during development of C. elegans. Described interaction between genes involved in sperm development is shown as Supplemental Fig. 2c. Cliques colored in red are induced upon RNAi while cliques in blue are repressed. The linear regression function was generated with Microsoft Excel without weighting, a square value of 1 would indicate a perfect correlation between the cliques.

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