Table 5 HSP-90-responsive cliques with highest enrichment of daf-16 supported (red) and suppressed (blue) genes.

From: hsp-90 and unc-45 depletion induce characteristic transcriptional signatures in coexpression cliques of C. elegans

Up1

Up2

Down1

Down2

Down3

Down4

C10C5.2-Y58A7A.3

col-138-col-49

C46C2.5_15926-W03F11.1

C17E7.4-T06D4.1

vit-2-vit-4_22519

C17H12.6-swt-6

K08D10.9-F46A8.1

R12E2.14_75-R12E2.15

ZC373.2-Y62H9A.6_1596

fbxc-28-sdz-28

C10A4.6-C01A2.6

F55G11.8-dod-17

hsp-16.2-F44E5.4_19238

mlt-9_22518-F33D4.6_14044

C10C5.3-C10C5.5

sea-1-R04D3.4

fbxc-28-sdz-28

R10H10.3-T21H3.1

lys-3-tsp-1

col-117-col-167_1015

171971_x_at-D1054.11_184

ZK1053.4-C08F1.6

C17E7.4-T06D4.1

 

hpo-6-C49C3.9

col-146-col-133

C46C2.5_15925-F17E9.2

F11A3.2-F47G3.3

R07E4.5-skp-1_1608

 

C32F10.4-D1086.2

bus-8_3160-K04H4.2_2324

C03B1.14-F46C3.2

K09D9.12-T10C6.10

R10H10.3-T21H3.1

 

F13E6.1_2090-C35C5.3_1843

sqt-2-dpy-9

col-178-col-19

K05C4.4-fbxc-46

sre-33-ZK1025.1_8337

 

Y6G8.2_5650-F17B5.1

abu-7-abu-8_22491

T24D1.3-egg-1

fbxb-31-fbxb-119

  

fbxa-35-Y39A3A.3

agmo-1_5527-F53B1.4

 

Y116A8C.19-F38C2.7

  

C17H1.6-C17H1.13

dos-2-grd-2

 

npp-8_4368-E01B7.1_7741

  

ccg-1_12351-ZC410.5

R12A1.3-M195.2

 

sdz-10-fbxb-62

  

C17H12.6-swt-6

pqn-54-abu-9

 

fbxb-13-fbxb-24

  

F58F9.3_11574-R07B7.6

col-128-cdh-10_9234

 

skr-16-F37B4.10

  

T12G3.1_17-T12G3.1_18846

C38C6.3-acdh-6

 

dsh-1_3575-C40A11.4

  

W01F3.2_1554-Y106G6D.8

C36C5.12-F57G8.7

 

dos-2-grd-2

  
  1. Sorted according to the nomenclature estabilshed in Eckl et al., 2017, which grouped the hsp-90 responsive genes in two major groups for upregulation and four groups for downregulation based on co-expression network analysis. Cliques enriched within these groups are listed under the group names (Up1, Up2, Down1, Down2, Down3 and Down4). The groups are labeled in bold, if enrichment reaches the significance level of 1e-5 and they are colored, if the same group is found within the top daf-16 regulated groups. Coloring is red, if it is among upregulated DAF-16 targets and blue if, it is among down regulated DAF-16 targets.