Table 1 Baseline characteristics of study participants.

From: Colonic dialysis can influence gut flora to protect renal function in patients with pre-dialysis chronic kidney disease

Characteristic

Healthy subjects

Patients with chronic kidney disease

Colonic dialysis

No dialysis

N

34

25

25

Age (year)

52.62 ± 6.68

56.24 ± 11.7

51.08 ± 8.58

Male

16 (47.1)

12 (48)

13(52)

SBP (mmHg)

119.63 ± 18.69

138.72 ± 17.37*

136.04 ± 17.92#

DBP (mmHg)

77.50 ± 12.00

81.96 ± 9.01

79.32 ± 10.08

CKD stage

3–4 (eGFR 15–59)

0

10

13

5 (eGFR < 15)

0

15

12

Primary disease

CGN

0

9

16

DM

0

5

6

HT

0

7

0

SLE

0

1

0

AP

0

1

0

DPKD

0

0

1

Other

0

2

2

Colonic dialysis duration (year)

3.26 ± 2.52(0.6–8.5)

Colonic dialysis frequency (times per week)

3.33 ± 1.39(1–7)

Laboratory parameters

Hb (g/L)

141.97 ± 14.35

107.75 ± 20.87*

96.92 ± 25.50#

ALB(g/L)

46.06 ± 2.50

39.67 ± 5.59*

38.94 ± 8.00#

LDL (mmol/L)

3.29 ± 0.69

3.00 ± 0.76

3.16 ± 0.77

TG (mmol/L)

1.57 ± 0.90

2.30 ± 1.38*

2.19 ± 1.45#

TC (mmol/L)

5.27 ± 0.90

4.74 ± 1.18

5.06 ± 1.03

Glu (mmol/L)

5.98 ± 1.86

5.46 ± 1.29

6.36 ± 3.61

Urea (mmol/L)

5.29 ± 1.32

17.11 ± 6.93

16.37 ± 6.74

UA (mmol/L)

334.01 ± 80.22

431.18 ± 104.95*

443.14 ± 103.85#

K (mmol/L)

4.52 ± 0.60

4.64 ± 0.71

Ca (mmol/L)

2.21 ± 0.15

2.20 ± 0.19

P (mmol/L)

1.41 ± 0.30

1.46 ± 0.50

Mg (mmol/L)

0.86 ± 0.15

0.84 ± 0.10

Qualitative determination of urinary protein

Negative

30

1

1

Microscale

3

3

0

Positive

1

21

24

Medications at baseline

Calcium channel-blockers

17

11

ACE inhibitors/ARBs

8

9

Beta-blockers

10

7

Diuretics

2

2

Iron agents

3

5

Phosphate binders

0

0

EPO

5

7

Anticoagulants

7

6

Lipid-lowering drugs

6

5

Antidiabetic drugs

4

4

Other BP-lowering drugs

6

1

  1. Values are n, n (%), or mean ± SD, unless otherwise noted.
  2. SBP systolic blood pressure, DPB diastolic blood pressure, CKD chronic kidney disease, CGN chronic glomerulonephritis, DM diabetic mellitus, HT hypertension, SLE systemic lupus erythematosus, AP allergic purpura, PKD polycystic kidney disease, Hb hemoglobin, ALB albumin, LDL low density lipop-rotein, TG triglyceride, TC cholesterol, Glu glucose, UA uric acid, K potassium, Ca calcium, P phosphorus, Mg magnesium, EPO Erythropoietin. *p < 0.05 versus healthy subjects, #p < 0.05 versus healthy subjects.