Table 3 Clinicodemographic and laboratory values in 203,008 hemodialysis patients according to dialyzer type.

From: High-performance dialyzers and mortality in maintenance hemodialysis patients

 

I

II

III

IV

V

P value

n (%)

2087 (1.0)

1721 (0.9)

8349 (4.1)

165,082 (81.3)

25,769 (12.7)

 

Age (years)

74.9 ± 10.7

70.8 ± 12.1

67.4 ± 12.4

65.6 ± 12.3

61.0 ± 12.2

< 0.0001

Sex (% female)

57.8

49.2

41.0

39.4

32.0

< 0.0001

Dialysis vintage (years)

5 [3–8]

5 [3–10]

6 [3–11]

7 [4–12]

8 [4–14]

< 0.0001

Presence of DM (%)

38.1

34.5

34.5

33.7

28.7

< 0.0001

CVD comorbidity (%)

34.9

33.7

27.3

25.4

19.9

< 0.0001

    Coronary artery disease

8.2

9.9

7.5

7.4

6.2

 

    Ischemic stroke

23.2

22.1

17.6

15.2

11.1

 

    Hemorrhagic stroke

7.0

6.9

5.3

5.0

3.8

 

    Limb amputation

4.0

3.6

3.2

3.1

2.5

 

Body mass index (kg/m2)

19.6 ± 3.4

20.2 ± 3.4

20.9 ± 3.5

21.1 ± 3.5

21.6 ± 3.5

< 0.0001

Hemoglobin (g/dL)

10.0 ± 1.4

10.1 ± 1.3

10.3 ± 1.3

10.4 ± 1.3

10.5 ± 1.2

< 0.0001

Serum albumin (g/dL)

3.5 ± 0.5

3.6 ± 0.5

3.6 ± 0.5

3.7 ± 0.4

3.7 ± 0.4

< 0.0001

Calcium (mg/dL)

8.8 ± 0.8

8.9 ± 0.8

9.0 ± 0.8

9.0 ± 0.8

9.1 ± 0.8

< 0.0001

Phosphate (mg/dL)

4.9 ± 1.5

5.2 ± 1.5

5.2 ± 1.5

5.3 ± 1.5

5.5 ± 1.5

< 0.0001

β2-microglobulin (mg/L)

31.1 ± 10.2

29.4 ± 8.8

28.2 ± 7.5

27.0 ± 6.8

27.2 ± 6.6

< 0.0001

C-reactive protein (mg/dL)

0.18 [0.06–0.75]

0.18 [0.07–0.56]

0.14 [0.06–0.43]

0.12 [0.05–0.40]

0.10 [0.05–0.30]

< 0.0001

Kt/V

1.26 ± 0.29

1.26 ± 0.27

1.38 ± 0.29

1.41 ± 0.29

1.43 ± 0.30

< 0.0001

nPCR (g/kg/day)

0.84 ± 0.20

0.83 ± 0.18

0.87 ± 0.19

0.88 ± 0.18

0.90 ± 0.17

< 0.0001

SCI (mg/kg/day)

18.4 ± 2.7

19.1 ± 2.9

20.3 ± 3.0

20.9 ± 3.0

22.2 ± 2.9

< 0.0001

Mortality rate (/person-years)

0.24

0.17

0.10

0.08

0.05

< 0.0001

Mortality, n (%)

0.002

    All-cause

444 (21.3)

273 (15.9)

792 (9.5)

13,113 (7.9)

1278 (5.0)

 

    Cardiovascular-related

152 (7.3)

123 (7.2)

323 (3.9)

5518 (3.3)

559 (2.2)

 

    Infection-related

99 (4.7)

46 (2.7)

167 (2.0)

2342 (1.4)

206 (0.8)

 

    Cancer-related

33 (1.6)

29 (1.7)

79 (0.9)

1210 (0.7)

131 (0.5)

 

    Others

160 (7.7)

75 (4.4)

223 (2.7)

4043 (2.4)

382 (1.5)

 
  1. CVD cardiovascular disease, DM diabetes mellitus, nPCR normalized protein catabolic rate, SCI simplified creatinine index.