Table 3 Clinicodemographic and laboratory values in 203,008 hemodialysis patients according to dialyzer type.
From: High-performance dialyzers and mortality in maintenance hemodialysis patients
I | II | III | IV | V | P value | |
---|---|---|---|---|---|---|
n (%) | 2087 (1.0) | 1721 (0.9) | 8349 (4.1) | 165,082 (81.3) | 25,769 (12.7) | |
Age (years) | 74.9 ± 10.7 | 70.8 ± 12.1 | 67.4 ± 12.4 | 65.6 ± 12.3 | 61.0 ± 12.2 | < 0.0001 |
Sex (% female) | 57.8 | 49.2 | 41.0 | 39.4 | 32.0 | < 0.0001 |
Dialysis vintage (years) | 5 [3–8] | 5 [3–10] | 6 [3–11] | 7 [4–12] | 8 [4–14] | < 0.0001 |
Presence of DM (%) | 38.1 | 34.5 | 34.5 | 33.7 | 28.7 | < 0.0001 |
CVD comorbidity (%) | 34.9 | 33.7 | 27.3 | 25.4 | 19.9 | < 0.0001 |
Coronary artery disease | 8.2 | 9.9 | 7.5 | 7.4 | 6.2 | |
Ischemic stroke | 23.2 | 22.1 | 17.6 | 15.2 | 11.1 | |
Hemorrhagic stroke | 7.0 | 6.9 | 5.3 | 5.0 | 3.8 | |
Limb amputation | 4.0 | 3.6 | 3.2 | 3.1 | 2.5 | |
Body mass index (kg/m2) | 19.6 ± 3.4 | 20.2 ± 3.4 | 20.9 ± 3.5 | 21.1 ± 3.5 | 21.6 ± 3.5 | < 0.0001 |
Hemoglobin (g/dL) | 10.0 ± 1.4 | 10.1 ± 1.3 | 10.3 ± 1.3 | 10.4 ± 1.3 | 10.5 ± 1.2 | < 0.0001 |
Serum albumin (g/dL) | 3.5 ± 0.5 | 3.6 ± 0.5 | 3.6 ± 0.5 | 3.7 ± 0.4 | 3.7 ± 0.4 | < 0.0001 |
Calcium (mg/dL) | 8.8 ± 0.8 | 8.9 ± 0.8 | 9.0 ± 0.8 | 9.0 ± 0.8 | 9.1 ± 0.8 | < 0.0001 |
Phosphate (mg/dL) | 4.9 ± 1.5 | 5.2 ± 1.5 | 5.2 ± 1.5 | 5.3 ± 1.5 | 5.5 ± 1.5 | < 0.0001 |
β2-microglobulin (mg/L) | 31.1 ± 10.2 | 29.4 ± 8.8 | 28.2 ± 7.5 | 27.0 ± 6.8 | 27.2 ± 6.6 | < 0.0001 |
C-reactive protein (mg/dL) | 0.18 [0.06–0.75] | 0.18 [0.07–0.56] | 0.14 [0.06–0.43] | 0.12 [0.05–0.40] | 0.10 [0.05–0.30] | < 0.0001 |
Kt/V | 1.26 ± 0.29 | 1.26 ± 0.27 | 1.38 ± 0.29 | 1.41 ± 0.29 | 1.43 ± 0.30 | < 0.0001 |
nPCR (g/kg/day) | 0.84 ± 0.20 | 0.83 ± 0.18 | 0.87 ± 0.19 | 0.88 ± 0.18 | 0.90 ± 0.17 | < 0.0001 |
SCI (mg/kg/day) | 18.4 ± 2.7 | 19.1 ± 2.9 | 20.3 ± 3.0 | 20.9 ± 3.0 | 22.2 ± 2.9 | < 0.0001 |
Mortality rate (/person-years) | 0.24 | 0.17 | 0.10 | 0.08 | 0.05 | < 0.0001 |
Mortality, n (%) | 0.002 | |||||
All-cause | 444 (21.3) | 273 (15.9) | 792 (9.5) | 13,113 (7.9) | 1278 (5.0) | |
Cardiovascular-related | 152 (7.3) | 123 (7.2) | 323 (3.9) | 5518 (3.3) | 559 (2.2) | |
Infection-related | 99 (4.7) | 46 (2.7) | 167 (2.0) | 2342 (1.4) | 206 (0.8) | |
Cancer-related | 33 (1.6) | 29 (1.7) | 79 (0.9) | 1210 (0.7) | 131 (0.5) | |
Others | 160 (7.7) | 75 (4.4) | 223 (2.7) | 4043 (2.4) | 382 (1.5) |