Table 1 Antibacterial activity of newly predicted peptide on normal (upper) or drug resistant bacteria (lower).

From: BING, a novel antimicrobial peptide isolated from Japanese medaka plasma, targets bacterial envelope stress response by suppressing cpxR expression

Bacteria

Gram (+/−)

MIC* (µg/mL)

Streptococcus Faecalis

+

50

Streptococcus pyogenes ATCC 14289

+

50

Staphylococcus aureus ATCC 6538

+

20

Bacillus subtilis 168

+

16

Staphylococcus aureus ATCC 29213

+

64

Aeromonas hydrophila ATCC 49140

−

20

Vibrio alginolyticus ATCC 33840

−

50

Edwardsiella tarda PE210

−

10

E. cloacae BAA-1143

−

32

Acinetobacter baumannii ATCC 19606

−

10

Escherichia coli ATCC 10536

−

5

Escherichia coli (pathogenic)

−

5

Escherichia coli BL21 (DE3)

−

8

Klebsiella pneumoniae (NDM-1) ATCC BAA-2470

−

32

Escherichia coli (NDM-1) ATCC BAA-2469

−

16

NDM-1/BL21 (DE3)

−

4

SHV-1/BL21 (DE3)

−

4

TEM-1/BL21 (DE3)

−

8

MCR-1/BL21 (DE3)

−

16

Methicillin-resistant S. aureus ATCC BAA-41

+

32

Multidrug-resistant S. aureus ATCC BAA-44

+

32

Staphylococcus epidermidis ATCC 12228

+

4

Pseudomonas aeruginosa A

−

50

  1. *MIC: the lowest concentration of an antimicrobial agent that can inhibit the growth of bacteria after overnight incubation.