Figure 2
From: Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse
Histopathological assessment of kidney in mice treated with pan-LOX and LOXL2 inhibitors. (A) Representative images of histological staining; (B) Masson-Trichrome score reflecting tubular dilatation, inflammation and fibrosis (n = 5); (C) PAS score reflecting glomerulosclerosis (n = 7); (D) Pico-Sirius Red (PSR) staining (n = 7–10) . Data are expressed as Mean ± SEM. Vs Ctrl: *P < 0.05, **P < 0.01, ***P < 0.001; vs CsA: #P < 0.05, ###P < 0.001. Scale bar = 200 μm.
