Figure 3

Adjusted HRs for risk of dementia according to baseline (A) SBP and (B) DBP measured in different age subgroups. Spline curves represent HRs adjusted for age, sex, income, body mass index, alcohol consumption, smoking, physical activity, hypothyroidism, hyperthyroidism, major bleeding, atrial fibrillation, heart failure, diabetes mellitus, dyslipidemia, myocardial infarction, peripheral artery disease, chronic kidney disease, chronic obstructive pulmonary disease, liver disease, malignant neoplasm, and medication at baseline (e.g. aspirin, statin, oral anticoagulant, ß-blocker, RAAS blocker, calcium channel blocker, diuretics and alpha blocker). Subjects with baseline SBP 120 mmHg or DBP 80 mmHg were used as reference. CI confidence interval, DBP diastolic blood pressure, HR hazard ratio, SBP systolic blood pressure.