Figure 5

The gut microbiota profiles of SCI patients stratify by AIS score and severity of injury. Principal Coordinates Analysis based on Bray–Curtis distances between the genus-level microbial profiles of SCI patients according to AIS score (A) and SCI severity (B). A significant separation by both covariates was found (p ≤ 0.04, permutation test with pseudo-F ratios). More severity, AIS score A or B and neurological level of lesion between C1 to C6 and C7 to T6; less severity, AIS score A or B and lesion level between T7 and L5, and AIS score C or D and every neurological level of lesion. Box plots showing the distribution of the relative abundance values of discriminatory genera by AIS score (C) and SCI severity (D). p ≤ 0.05, Wilcoxon rank sum test.