Table 2 Demographic data classified according to outcome.

From: Tc-99m GSA scintigraphy within the first 3 days after admission as an early predictor of outcome in severe acute liver injury

 

Died/liver transplantation (n = 16)

Survived (n = 53)

P-value

Age, median (y)

64.5 (50.0–68.8)

56.0 (37.0–67.0)

0.1436

Male:female

9:7

22:31

0.3924

Development of HE during the clinical course

5/16

0/48

0.0006

AST (U/L)

463 (131.8–1318)

1169 (362–2086)

0.1740

ALT (U/L)

637 (94.8–1733.5)

1372 (453–2360.5)

0.0545

Total bilirubin (mg/dL)

18.2 (12.4–21.4)

7.8 (2.7–16.3)

0.0023

PT-INR

2.13 (1.69–3.20)

1.80 (1.58–2.00)

0.0146

MELD score

12.8 (12.4–17.3)

11.0 (8.8–12.2)

< 0.0001

LHL15

0.686 (0.619–0.734)

0.836 (0.779–0.876)

< 0.0001

HH15

0.842 (0.803–0.90)

0.760 (0.702–0.804)

0.0001

  1. Data are presented as n (%) or median (interquartile range [IQR]).
  2. HE hepatic encephalopathy, AST aspartate aminotransferase, ALT alanine aminotransferase, PT-INR prothrombin time-international normalized ratio, MELD model for end-stage liver disease, LHL15 Hepatic accumulation index calculated by dividing the radioactivity of the liver regions of interest by that of the liver-plus-heart regions of interest at 15 min. HH15, Blood clearance index calculated by dividing the radioactivity of the heart regions of interest at 15 min by that at 3 min.