Table 3 Cox regressions for CKD by risk exposures.

From: An observational claims data analysis on the risk of maternal chronic kidney disease after preterm delivery and preeclampsia

Outcome

Exposure

HR

95% CI HR

z

P( >|z|)

Any CKD1,2

Preeclampsia alone5

1.784

[1.516; 2.098]

6.981

 < .001

Preterm delivery alone5

1.789

[1.531; 2.091]

7.316

 < .001

Both/joint risk exposure(s)5

5.227

[4.201; 6.504]

14.828

 < .001

Maternal age

1.051

[1.042; 1.060]

11.619

 < .001

Diabetes

1.470

[1.320; 1.638]

7.014

 < .001

Obesity

1.609

[1.453; 1.781]

9.138

 < .001

Mild to moderate CKD1,3

Preeclampsia alone5

1.753

[1.471; 2.089]

6.268

 < .001

Preterm delivery alone5

1.806

[1.529; 2.133]

6.956

 < .001

Both risk exposures5

5.138

[4.060; 6.502]

13.626

 < .001

Maternal age

1.056

[ 1.047; 1.066]

11.874

 < .001

Diabetes

1.483

[1.322; 1.665]

6.698

 < .001

Obesity

1.635

[1.465; 1.823]

8.817

 < .001

Severe CKD1,4

Preeclampsia alone5

2.971

[1.874; 4.711]

4.630

 < .001

Preterm delivery alone5

4.705

[3.259; 6.794]

8.263

 < .001

Both risk exposures5

11.903

[6.902; 20.528]

8.907

 < .001

Maternal age

1.021

[0.995; 1.048]

1.572

0.116

Diabetes

1.181

[0.832; 1.674]

0.931

0.352

Obesity

1.479

[1.074; 2.035]

2.400

0.016

  1. z = z-Value; P( >|z|) = empirical significance level.
  2. CKD Chronic kidney disease, HR Hazard ratio, 95% CI HR 95% confidence interval of hazard ratio.
  3. 1N = 257,481.
  4. 2Number of events = 1.821.
  5. 3Number of events = 1.577.
  6. 4Number of events = 190.
  7. 5Reference group = no exposure either to preterm delivery or to preeclampsia.
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