Figure 1

Flow diagram of participants and measurements within the EnCoRe study and the number of post-treatment measurements included in the analyses presented in this paper. Data collected up until November 1st 2016 were included in the analyses. ¹ Totals do not add up because some individuals reported multiple reasons for non-participation. ² Response rate = (persons with home visits)/(persons with home visits + persons lost to follow-up – persons died). The declining numbers of participants at subsequent time points are predominantly due to the fact that not all participants had reached yet these time points on November 1st 2016. ³ Since the current analysis was focused on physical activity and metabolites after colorectal cancer treatment, only post-treatment measurements with available data on self-reported physical activity, metabolites and covariates were included. A total of n = 252 participants with at least one post-treatment measurement including these data were included in the analysis. The number of participants with available physical activity and metabolites data were respectively n = 268 and n = 249 at 6 weeks, n = 215 and n = 203 at 6 months, n = 169 and n = 162 at 1 year, and n = 72 and n = 73 at 2 years post-treatment. ⁴ Other person who also missed 6 weeks visit did not have follow-up visit before November 1st 2016.