Figure 2 | Scientific Reports

Figure 2

From: Peritumoral edema in breast cancer at preoperative MRI: an interpretative study with histopathological review toward understanding tumor microenvironment

Figure 2

Preoperative breast MR images in a 54-year-old woman with invasive ductal carcinoma. (a) Fat-suppressed T1-weighted axial contrast-enhanced images shows a 4 cm mass in the left breast. (b) Fat-suppressed T2-weighted axial image shows peritumoral edema seen as high signal intensity surrounding the tumor (arrows). Microscopic pictures demonstrated a moderate grade of lymphovascular invasion (c, indicated by black arrowheads), a moderate grade of vessel ectasia (d, indicated by black arrows), a marked grade of stromal fibrosis (e, indicated by white asterisks), and a ≥ 30% of tumor necrosis (f, indicated by black asterisks) (hematoxylin–eosin stain; original magnification, ce × 100; and f × 200).

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