Table 2 Detailed histopathological characteristics associated with peritumoral edema.
Characteristics | All patients | Patients without peritumoral edema (n = 102) | Patients with peritumoral edema (n = 34) | P value* |
|---|---|---|---|---|
Lymphovascular invasion | < 0.001 | |||
1 (Absent) | 29 (21.3) | 28 (27.5) | 1 (2.9) | |
2 (Mild) | 24 (17.6) | 18 (17.6) | 6 (17.6) | |
3 (Moderate) | 50 (36.8) | 38 (37.3) | 12 (35.3) | |
4 (Marked) | 33 (24.3) | 18 (17.6) | 15 (44.1) | |
Vessel ectasia | < 0.001 | |||
1 (Absent) | 2 (1.5) | 2 (2.0) | 0 (0.0) | |
2 (Mild) | 23 (16.9) | 21 (20.6) | 2 (5.9) | |
3 (Moderate) | 68 (5.0) | 58 (56.9) | 10 (29.4) | |
4 (Marked) | 43 (31.6) | 21 (20.6) | 22 (64.7) | |
Stromal fibrosis | 0.003 | |||
1 (Absent) | 60 (44.1) | 50 (49.0) | 10 (29.4) | |
2 (Mild) | 54 (39.7) | 41 (40.2) | 13 (38.2) | |
3 (Moderate) | 21 (15.4) | 11 (10.8) | 10 (29.4) | |
4 (Marked) | 1 (0.7) | 0 (0.0) | 1 (2.9) | |
Growth pattern | < 0.001 | |||
1 (Expanding) | 4 (2.9) | 3 (2.9) | 1 (2.9) | |
2 (Infiltrative, mild) | 4 (2.9) | 1 (1.1) | 3 (8.8) | |
3 (Infiltrative, moderate) | 30 (22.1) | 14 (13.7) | 16 (47.1) | |
4 (Infiltrative, marked) | 98 (72.1) | 84 (82.4) | 14 (41.2) | |
Tumor necrosis | < 0.001 | |||
1 (Absent) | 106 (77.9) | 95 (93.1) | 11 (32.4) | |
2 (≤ 10%) | 8 (5.9) | 2 (2.0) | 6 (17.6) | |
3 (≤ 20%) | 20 (14.7) | 5 (4.9) | 15 (44.1) | |
4 (> 20%) | 2 (1.5) | 0 (0.0) | 2 (5.9) | |
Tumor budding | 0.72 | |||
1 (Absent) | 11 (8.1) | 10 (9.8) | 1 (2.9) | |
2 (Low) | 24 (17.6) | 17 (16.7) | 7 (20.6) | |
3 (Intermediate) | 40 (29.4) | 25 (24.5) | 15 (44.1) | |
4 (High) | 61 (4.9) | 50 (49.0) | 11 (32.4) | |
Tumor infiltrating lymphocytes | 0.16 | |||
1 (≤ 10%) | 93 (68.4) | 76 (74.5) | 17 (50.0) | |
2 (≤ 20%) | 19 (14.0) | 10 (9.8) | 9 (26.5) | |
3 (≤ 30%) | 15 (11.0) | 9 (8.8) | 6 (17.6) | |
4 (≤ 40%) | 3 (2.2) | 2 (2.0) | 1 (2.9) | |
5 (> 40%) | 6 (4.4) | 5 (4.9) | 1 (2.9) | |
