Figure 5 | Scientific Reports

Figure 5

From: Identification, characterization and control of a sequence variant in monoclonal antibody drug product: a case study

Figure 5

Imaged capillary electrophoresis isoelectric focusing (iCE) profiles of mAb X lots and mAb X’ (a) before and, (b) after CPB digestion. The lysine variant peaks disappeared post CPB digestion (indicated with arrows). (c) HIC profiles of mAb X lots and mAb X’ showing the relatively higher hydrophilicity of mAb X’. mAb X sourced from external agencies are labelled as mAb X2.

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