Table 4 Description of studies that evaluated contrast sensitivity and higher-order aberrations in keratoconus subjects.
From: Contrast sensitivity and higher-order aberrations in Keratoconus subjects
Applegate et al. 200020 | Okamoto et al. 200827 | Bilen et al. 201628 | Current study | |
|---|---|---|---|---|
Control (N) | 13 (13P) | 26 (13P) | No | 35 (35P) |
KC (N) | 8 (8P) | 22 (14P) | 71 (71P) | 38 (22P) |
KC (severity) | No data | No data | Early to moderate | Subclinical and Mild (grade 1–2) |
Mean age of KC subjects (years) | No data | 30.5 ± 8.4 No data | 28.3 ± 8.3 14–54 | 25.6 ± 5.0 17–38 |
LogMar VA of KC group (range) | No data | 0.04 ± 0.17 0.30 to − 0.10 | 0.25 ± 0.21 1.00 to 0.00 | 0.08 ± 0.12 0.50 to 0.00 |
Separate analysis for KC group with 0.00 LogMar BCVA | No | No | No | Yes |
Pupil dilation | Yes | Yes | No | No |
Pupil size (mm) | 3 and 7 | 6 | 6 | 5 |
Aberrometry method | Calculated | Measured | Calculated | Measured |
CS target | Horizontal sinusoidal bars | Letter | Letter | Vertical Gabor patches |
CS method | Two alternative forced choice | CSV-1000LV chart | Hamilton-Veale chart | Two alternative forced choice |
Main findings for KC: HOA and CS | Negative correlation between corneal aberration and CS | Negative correlation between CS and Third and Forth order aberration | Negative correlation between CS and total RMS and vertical coma HOA | Negative correlated between CS and HOA in KC group with 0.00 LogMar VA |
