Figure 2 | Scientific Reports

Figure 2

From: An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency

Figure 2

Deduced epitope locations on a ribbon diagram of the DENV-2 E protein. The deduced epitope locations were plotted on a DENV-2 E dimer, based on the data provided by the Protein Data Bank accession number 1OAN. DI, DII, and DIII are indicated in red, yellow, and blue, respectively. The fusion loop region (98–110) is colored in green. Mutations affecting reactivity with the HuMAbs are shown as green spheres and in the magnified square.

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