Figure 3 | Scientific Reports

Figure 3

From: Anethole induces anti-oral cancer activity by triggering apoptosis, autophagy and oxidative stress and by modulation of multiple signaling pathways

Figure 3

Anethole inhibits the migration of oral cancer cells. (A) Mouth epidermoid carcinoma cells (Ca9-22) were cultured up to 100% confluence. Scratches were then made on each monolayer and cells were incubated with or without anethole. Cell migration/wound repair were observed over time (0, 6, 12 and 24 h) and pictures were taken. Wound closure was measure by the distance, at 3 separate sites, between opposite edges of it. Results are reported as the means (%) ± SD (n = 3). (B) Graphs displaying the three experiments of a cell lesion assay on Ca9-22 incubated with or without anethole 3 μM. (C) Western blotting of E-cadherin and vimentin after being exposed for 24 h, with or without anethole (10 μM) (n = 3).

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