Table 3 Mortality predictive value of viremia compared to other factors.

From: Detection of SARS-CoV-2 RNA in serum is associated with increased mortality risk in hospitalized COVID-19 patients

 

Model 1

Model 2

Model 3

Model 4

HR

p

HR

p

HR

p

HR

P

qSOFA

0.92

N.S.

N.I.

–

N.I.

–

N.I.

–

CURB65

1.06

N.S.

N.I.

–

N.I.

–

N.I.

–

Low Ly

1.85

0.080

–

–

1.85

0.091

1.37

0.388

High IL-6

1.95

0.055

1.74

0.121

–

–

1.45

0.304

High LDH

2.74

0.005

2.74

0.008

2.57

0.011

–

–

Viremia TFS

13.5

 < 0.001

11.30

 < 0.001

10.4

 < 0.001

9.87

 < 0.001

Viremia Roche

8.38

 < 0.001

6.84

 < 0.001

6.69

 < 0.001

7.09

 < 0.001

  1. CURB65: confusion-urea-respiratory rate-blood pressure-65-years-old index; HR: Hazard Ratio; p: p-value; N.S.: not significant; N.I.: not included; Low Ly.: low total lymphocyte count; IL-6: interleukin-6; LDH: lactate dehydrogenase; qSOFA: quick sepsis related organ failure assessment; TFS: Thermo Fisher Scientific. Model 1 adjusted by age, sex and Charlson index. Model 2 adjusted by age, sex, Charlson index and low total lymphocyte count. Model 3 adjusted by age, sex, Charlson index and high IL-6. Model 4 adjusted by age, sex, Charlson index and high LDH.
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