Table 1 Peptides selected by OncoPeptVAC for use in T-cell activation assays.
Peptide ID | # Class-I HLA restriction | #Class-II HLA restriction | OncoPeptVAC score for individual HLAs (range) | Class-I binding percentile rank (range) | Class-II binding percentile rank (range) | Presence in spike peptide pools | Other features |
|---|---|---|---|---|---|---|---|
Pep-1 | 3 | 0 | 0.21–0.51 | 0.27–0.77 | NA | Yes | One contact residue for neutralizing Ab |
Pep-2 | 0 | 2 | NA | NA | 7.6–7.8 | No | 4 ACE contact residues and 2 contact residues for neutralizing Ab |
Pep-3 | 1 | 3 | 0.27 | 0.83 | 1.5–8.5 | No |  |
Pep-4 | 7 | 9 | 0.43–0.94 | 0.02–0.25 | 0.58–10.0 | No |  |
Pep-5 | 2 | 1 | 0.24–0.28 | 0.45–0.49 | 3.1 | Yes | 4 ACE contact residues |
Pep-6 | 6 | 10 | 0.28–0.9 | 0.37–0.97 | 0.27–9.6 | No |  |
Pep-7 | 11 | 18 | 0.21–0.94 | 0.06–0.8 | 0.49–9.3 | Yes |  |
Pep-8 | 14 | 16 | 0.21–0.7 | 0.01–0.87 | 0.97–10.0 | No |  |
Pep-9 | 27 | 13 | 0.22–0.96 | 0.02–0.89 | 1.8–8.8 | No |  |
Pep-10 | 4 | 9 | 0.23–0.83 | 0.19–0.71 | 0.45–8.8 | No | 5 ACE contact residues and 2 contact residues for neutralizing Ab |
Pep-11 | 6 | 2 | 0.22–0.88 | 0.44–0.9 | 7.2–8.0 | No |  |
