Figure 4

Intrinsic disorder predisposition of Nucleoprotein (N). (A) The intrinsic disorder profile generated for Nucleoprotein by a set of disorder predictors; PONDR VSL2, PONDR VL3, PONDR VLXT, PONDR FIT, IUPred2_long, and IUPred2_short are represented by black, red, blue, magenta, dark yellow-, and navy-colored straight lines respectively. A mean disorder profile calculated by averaging the outputs of seven predictors is represented by the green-colored short-dash line. Light green region around mean curve represents the error distribution for the mean. (B) MoRFs prediction through MoRFCHiBi_Web and ANCHOR. Dashed cyan line (0.5) represents cut-off for ANCHOR and dashed blue line (0.725) represents cut-off for MCW server. The area with light magenta color represents MoRF region predicted by MCW server. (C) Full-length modelled structure for N protein using I-Tasser web server. Red colored regions are predicted to be disordered based on the calculated mean. The N- and C-terminals are shown with arrows in the structure.