Figure 5
(a) The comparison of levels of interleukins (IL-6, IL-10, IL-12p70), interferon-γ (IFN-γ), monocyte chemoattractant protein-1 (MCP-1) and tumour necrosis factor α (TNF-α) in spleen of wild-type (WT) mice treated with LPS (n = 5), APdE9 mice with (n = 6) and without (n = 6) treatment with LPS versus WT control (n = 5). (b) The comparison of levels of IL-6, IL-10, MCP-1, IFN-γ, TNF-α and IL-12p70 in plasma of wild-type (WT) mice treated with LPS (n = 5), APdE9 mice with (n = 6) and without (n = 6) treatment with LPS versus WT control (n = 5). The data is presented as mean ± SD. Asterisks denote a statistically significant difference from the respective control (*p < 0.05, one-way ANOVA followed by Dunnett’s multiple comparisons test).
