Figure 2 | Scientific Reports

Figure 2

From: Influence of sub-inhibitory concentrations of antimicrobials on micrococcal nuclease and biofilm formation in Staphylococcus aureus

Figure 2

Biomass, polysaccharides and micrococcal nuclease (MN) activity of S. aureus ATCC12600, Newman lux, and Newman lux Δnuc1 biofilms under antimicrobial pressure (at 0, 1/8, \({\raise0.7ex\hbox{$1$} \!\mathord{\left/ {\vphantom {1 4}}\right.\kern-\nulldelimiterspace} \!\lower0.7ex\hbox{$4$}}\), \({\raise0.7ex\hbox{$1$} \!\mathord{\left/ {\vphantom {1 2}}\right.\kern-\nulldelimiterspace} \!\lower0.7ex\hbox{$2$}}\) or 1 times MBIC). All data are normalized to a control culture without antimicrobials (= 100%; horizontal dotted line). No MBIC was found for resveratrol, therefore it is set at the highest attainable concentration, 512 μg/mL. Statistical differences were calculated using an ANOVA. *Significant difference for concentrations smaller than MBIC when compared to the culture without antibiotics. (*p < 0.05; **p < 0.01; ***p < 0.001).

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