Table 1 Demographic and clinical parameters of TB patients and healthy donors.

From: PGE2 displays immunosuppressive effects during human active tuberculosis

Characteristic

TB patients

Healthy donors

n

40

53

Age

26.3 ± 1.4

27.3 ± 1.9

Sex (n = 40 and 53)

Male

16 (40%)

24 (45,3%)

Female

24 (60%)

29 (54,7%)

Ethnicity (n = 40 and 53)

Caucasian (European lineages)

15 (37,50%)

32 (60,4%)

American Indian

24 (60%)

21 (39,6%)

Asian

1 (2,5%)

–

AFB in sputum smear (n = 39)

AFB -

3 (7,69%)

–

AFB + 

18 (46,15%)

–

AFB + + 

10 (25,64%)

–

AFB + + + 

8 (20,51%)

–

Radiological lesions (n = 27)

Severe

13 (48,15%)

–

Moderate

11 (40,74%)

–

Mild

3 (11,11%)

–

Time of disease evolution (months)

2,21 ± 0,24

–

Extra-pulmonary TB (n = 40)

Yes

2 (5%)

–

No

38 (95%)

–

Immunological classification (n = 40)

High responders

14 (35,0%)

–

Low responders

15 (37,5%)

–

N/D

11 (27,5%)

–

  1. Acid-Fast Bacilli (AFB) in sputum smear represent: AFB-, 0 bacilli count; AFB + , 1–9 bacilli/100 fields; AFB + + , 1–9 bacilli/10 fields; AFB + + + , 1–9 bacilli/field. Radiological lesions: "mild" corresponds to patients with a single lobe involved and without visible cavities; "moderate" relates to patients presenting unilateral involvement of two or more lobes with cavities, if present, reaching a total diameter no greater than 4 cm; "severe" corresponds to bilateral disease with massive affectation and multiple cavities. Clinical symptoms analyzed in TB patients previous to hospital admission to establish the time (months) of disease evolution were: weight loss, night sweats, symptoms of malaise or weakness, persistent fever, presence of cough, history of shortness of breath, and hemoptysis. Continuous data are expressed as mean ± SEM, and categorical data are expressed as number (percentages).
Back to article page