Table 1 Pre- and postoperative characteristics of patients who underwent isolated HTx according to perioperative RRT support.

From: Impact of preoperative renal replacement therapy on the clinical outcome of heart transplant patients

Characteristics

Group 1 (n = 361)

Group 2 (n = 17)

Group 3 (n = 53)

Group 4 (n = 57)

P

PreRRT (−)

PreRRT (+)

PreRRT (−)

PreRRT (+)

PostRRT (−)

PostRRT (−)

PostRRT (+)

PostRRT (+)

Age, years

55 (44–62)

56 (49–65)

53 (40–60)

54 (46–61)

0.283

Male, n (%)

247 (67.9)

40 (74.1)

19 (79.2)

43 (72.9)

0.448

Height, cm

167 (150–171)

167 (163–176)

168 (160–172)

168 (160–172)

0.738

Weight, kg

61.7 (53.8–68.3)

62.9 (55.1–70.0)

61.1 (53.7–70.0)

63.4 (55.0–76.5)

0.674

Body mass index, kg/m2

22.2 (20.0–24.5)

22.1 (19.8–24.3)

23.1 (20.3–24.5)

23.5 (19.4–25.8)

0.649

Etiology of cardiomyopathy

Ischemic

65 (18.0)

2 (11.8)

10 (18.9)

19 (33.3)

0.045

Idiopathic dilated

205 (56.8)

10 (58.8)

27 (50.9)

21 (36.8)

0.041

Hypertrophic

24 (6.6)

0 (0)

5 (9.4)

0 (0)

0.104

Valvular heart disease

16 (4.4)

0 (0)

2 (3.8)

(1.8)

0.644

Comorbidities

Hypertension

107 (29.6)

4 (2.7)

16 (30.2)

21 (36.8)

0.660

Diabetes mellitus

95 (26.3)

6 (35.3)

15 (28.3)

22 (38.6)

0.078

Insulin requiring diabetes mellitus

20 (5.5)

2 (11.8)

5 (9.4)

7 (12.3)

0.194

Preoperative echocardiography

 LV EF, %

24 (18–30)

25 (18–32)

21 (18–32)

20 (15–26)

0.922

 LV EDD, mm

58 (48–67)

64 (54–71)

67 (50–76)

62 (52–73)

0.586

 LA volume index, ml/m2

72 (53–95)

61 (50–76)

77 (59–95)

67 (41–83)

0.586

 Septal E/e’

18.3 (12.8–24.2)

23.2 (12.6–34.4)

17.8 (14.9–23.0)

20.5 (16.6–29.3)

0.322

 RVSP, mmHg

39 (27–51)

46 (33–56)

47 (34.0–63)

44.0 (29.0–55.0)

0.015

PreHTx mechanical cardiac support

77 (21.2)

14 (82.4)

20 (37.2)

44 (77.2)

 < 0.001

 ECMO

70 (19.4)

13 (76.5)

20 (37.7)

43 (75.4)

 < 0.001

 LVAD

6 (1.7)

0 (0)

0 (0)

1 (1.8)

0.755

 IABP

1 (0.3)

1 (5.9)

0 (0)

0 (0)

0.004

PreHTx CRRT without previous history of RRT

0 (0)

12 (70.6)

0 (0)

46 (80.7)

 < 0.001

PreHTx mechanical ventilator

42 (11.6)

12 (70.6)

19 (35.8)

42 (73.7)

 < 0.001

Waiting time since HTx enlisting, days

80 (32–170)

18 (7–56)

39 (13–175)

19 (7–55)

0.004

  1. Data were expressed as median (IQR) or number (%).
  2. RRT renal replacement therapy, DM diabetes mellitus, LV left ventricle, eGFR estimated glomerular filtration rate, HTx heart transplantation, LV left ventricle, EF ejection fraction, EDD end-diastolic dimension, LA left atrium, E early mitral inflow velocity, e′ early mitral tissue Doppler velocity, RVSP right ventricular systolic pressure, ECMO extracorporeal membrane oxygenation, LVAD left ventricular assisting device, IABP intra-aortic balloon pump, RRT renal replacement therapy, EF ejection fraction, LV left ventricle, EDD end-diastolic dimension, CRRT continuous renal replacement.
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