Table 3 Univariable and multivariable analysis to predict progression to dialysis-dependent ESRD after HTx.

From: Impact of preoperative renal replacement therapy on the clinical outcome of heart transplant patients

Variables

Univariate

Multivariate

HR

95% CI

p

HR

95% CI

p

Age, year

1.016

0.988–1.046

0.265

1.009

0.987–1.054

0.385

Male

1.107

0.518–2.367

0.794

   

Diabetes mellitus

1.551

0.758–3.173

0.230

   

Insulin-dependent diabetes mellitus

4.866

2.013–11.764

 < 0.001

2.479

1.085–5.665

0.031

Preoperative mechanical ventilation

4.416

2.188–8.912

 < 0.001

0.801

0.296–2.169

0.663

Preoperative mechanical cardiac support

4.072

1.992–8.322

 < 0.001

1.612

0.570–4.558

0.368

Preoperative RRT

15.108

7.091–32.186

 < 0.001

2.327

0.969–5.648

0.062

Preoperative eGFR, ml/min/1.73 m2

0.971

0.957–0.985

0.001

0.994

0.980–1.008

0.410

Preoperative creatinine, mg/dL

2.852

1.844–4.411

 < 0.001

1.191

0.883–1.608

0.252

Cardiopulmonary bypass time, minutes

1.006

1.000–1.011

0.040

1.001

0.995–1.007

0.735

Cold ischemia time, minutes

1.000

1.012–1.023

0.956

   

Postoperative RRT

3.750

1.694–8.299

 < 0.001

8.982

2.928–27.552

 < 0.001

Primary graft failure

2.945

1.373–6.316

0.006

0.890

0.374–2.115

0.791

  1. RRT renal replacement therapy, eGFR estimated glomerular filtration rate, HTx heart transplantation, ESRD end-stage renal disease.
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