Table 2 Association and discriminant ability of TD-fNIRS parameters recorded at single hemisphere.

From: Monitoring the haemodynamic response to visual stimulation in glaucoma patients

TD-fNIRS parameters

OR

Est (95% C.I.)

Wald test

c index

Est (95% C.I.)

Df

χ2

p-value

τHHb

Left hemisphere

1.05 (0.90, 1.23)

1

0.614

 > 0.999

0.513 (0.400, 0.626)

Right hemisphere

0.93 (0.81, 1.07)

1

1.600

0.8220

0.555 (0.442, 0.668)

Ipsilateral hemisphere

1.01 (0.89, 1.15)

1

0.036

 > 0.999

0.524 (0.410, 0.623)

Contralateral hemisphere

0.97 (0.85, 1.10)

1

0.450

 > 0.999

0.548 (0.435, 0.660)

τO2Hb

Left hemisphere

0.89 (0.73, 1.08)

1

2.180

0.5592

0.586 (0.477, 0.696)

Right hemisphere

0.98 (0.81, 1.20)

1

0.046

 > 0.999

0.532 (0.421, 0.643)

Ipsilateral hemisphere

0.92 (0.75, 1.12)

1

1.110

 > 0.999

0.595 (0.486, 0.704)

Contralateral hemisphere

0.97 (0.84, 1.13)

1

0.228

 > 0.999

0.529 (0.418, 0.640)

AHHb

Left hemisphere

3.31 (0.35, 31.51)

1

1.770

0.7322

0.677 (0.503, 0.851)

Right hemisphere

12.63 (1.35, 117.74)

1

8.130

0.0174*

0.707 (0.517, 0.897)

Ipsilateral hemisphere

6.94 (0.95, 50.59)

1

6.000

0.0574

0.687 (0.508, 0.866)

Contralateral hemisphere

3.71 (0.78, 15.58)

1

4.470

0.1379

0.694 (0.511, 0.877)

AO2Hb

Left hemisphere

0.32 (0.11, 0.95)

1

6.890

0.0348*

0.691 (0.587, 0.795)

Right hemisphere

0.45 (0.23, 0.89)

1

8.490

0.0143*

0.699 (0.597, 0.802)

Ipsilateral hemisphere

0.53 (0.31, 0.89)

1

9.310

0.0091**

0.692 (0.589, 0.795)

Contralateral hemisphere

0.45 (0.21, 0.99)

1

6.390

0.0458*

0.695 (0.592, 0.798)

  1. Results obtained by estimating 16 distinct logistic models including a single independent variable. Each p-value and each confidence interval were adjusted for the multiplicity of tests using the Bonferroni rule. Column 1: TD-fNIRS parameters (A peak amplitude, τ = peak latency, O2Hb oxy-haemoglobin, HHb deoxy-haemoglobin). Column 2: estimated OR (Est estimates). Column 3: tests of association between parameters and pathological classification of eyes (Df degrees of freedom. χ2 Chi-square statistics. *p < 0.05; **p < 0.01). Column 4: estimates of the concordance index c.