Figure 5
From: Mucosa-associated gut microbiota reflects clinical course of ulcerative colitis
Flow chart showing the enrolled patients with ulcerative colitis (UC) and study protocols used in the present study. (A) Flow chart of 65 patients with UC initially enrolled in this study. Fourteen patients were excluded, and we analyzed a total of 51 patients with UC. They were classified into 2 groups: those with a Mayo endoscopic score (MES) of 0/1 (endoscopic remission group, n = 24) and those with an MES of 2/3 (endoscopically active group, n = 27). (B) Study protocol of the endoscopic remission group. After the biopsy samples for RNA-based 16S rRNA analysis had been obtained from the patients with an MES of 0/1 (n = 24), they were classified into 2 groups according to their later clinical course: non-relapse (n = 17) and relapse (n = 7). (C) Study protocol of the endoscopically active group. After the biopsy samples for RNA-based 16S rRNA analysis had been obtained from the patients with an MES of 2/3 (n = 27), they were classified into 3 groups according to their later clinical course: response (n = 6), refractory (n = 13), and non-response (n = 8).
