Figure 2
From: Concurrent YAP/TAZ and SMAD signaling mediate vocal fold fibrosis
TGF-β1 activated YAP/TAZ in HVOX. HVOX fibroblasts were treated with or without 10 ng/mL TGF-β1 for 24 h. Expression of ACTA2 (a), target genes of YAP/TAZ (b, CCN2; c CYR61; d EDN1; e FSTL1; f INHBA), YAP1 (g), and WWTR1 (h) were analyzed by qPCR (Data shown as mean ± SD; n = 3; *p < 0.05, Student’s t-test). YAP/TAZ nuclear localization was examined by immunostaining (i; bar = 50 µm).
