Table 2 Characteristics of the study population: women of childbearing age (Validation set—Group 2).

From: Exhaled volatilome analysis as a useful tool to discriminate asthma with other coexisting atopic diseases in women of childbearing age

 

Group 2 (n = 126)†

A-AD

NA

NA-AD

NA-NAD

Subjects n

14

111

47

64

Age (years) mean (range)

33.0 (25–39)

33.3 (18–42)

33.0 (18–42)

33.5 (22–41)

BMI (kg/m2) before pregnant mean (range)

23.50 (18.46–34.37)

23.28 (15.94–39.91)

23.35 (17.63–37.29)

23.23 (15.94–39.91)

Social class

Managers-technicians/skilled/semiskilled-unskilled/unemployed %

28.6/50.0/14.3/7.1

39.6/20.7/18.0/21.6

29.8/19.1/23.4/27.7

46.9/21.9/14.1/17.2

Educational level

Incomplete secondary or less/complete secondary/university %

7.1/35.7/57.1

11.7/28.8/59.5

14.9/31.9/53.2

9.4/26.6/64.1

Smoking during pregnancy, Yes/No n/n

2/12

14/97

4/43

10/54

Smoker, Yes/No n/n

3/11

13/98

6/41

7/57

Other atopic disorders, yes

14 (100%)b

47 (42%)a

47 (100%)

–

Allergic rhinitis, yes

14 (100%)b,c

34 (31%)a

34 (72%)a

–

Atopic dermatitis, yes

5 (36%)b

13 (12%)a

13 (28%)

–

Allergic conjunctivitis, yes

8 (57%)b

20 (18%)a

20 (43%)

–

Food allergy, yes

1 (7%)

7 (6%)

7 (15%)

–

Drug allergy, yes

3 (21%)

8 (7%)

8 (17%)

–

Parental asthma, yes

3 (21%)

12 (11%)

5 (11%)

7 (11%)

Parental allergic rhinitis, yes

7 (50%)

34 (31%)

19 (40%)

15 (23%)

Parental atopic dermatitis, yes

2 (14%)

11 (10%)

6 (13%)

5 (8%)

Antibiotics consumption, yes

1 (7%)

32 (29%)

12 (26%)

20 (31%)

Paracetamol consumption, yes

8 (57%)

67 (60%)

31 (66%)

36 (56%)

Inhaled corticosteroids consumption, yes

2 (14%)b,d

1 (1%)a

1 (2%)

0 (0%)a

Injectable corticosteroids consumption, yes

0 (0%)

2 (2%)

1 (2%)

1 (2%)

Blood leucocyte count /µl, mean (range)

8537 (7050–11,570)

9268 (5180–15,310)

9258 (5760–14,090)

9276 (5180–15,310)

Blood monocyte count /µl, mean (range)

630 (450–960)

595 (320–1280)

601 (360–1030)

590 (320–1280)

Blood lymphocyte count /µl, mean (range)

2035 (1270–2650)

2002 (990–3790)

1988 (1110–3790)

2013 (990–3700)

Blood basophil count /µl, mean (range)

34 (20–60)

34 (0–90)

37 (10–80)

33 (0–90)

Blood eosinophil count /µl, mean (range)

234 (90–510)b,c,d

146 (20–430)a

159 (20–430)a

135 (30–430) a

Blood neutrophil count /µl, mean (range)

5604 (4390–8320)

6491 (3470–10,990)

6473 (3510–9790)

6504 (3470–10,990)

Season at sampling

Winter/spring/summer/autumn %

0.0/35.7/35.7/28.6

3.6/32.4/41.4/22.5

2.1/36.2/38.3/23.4

4.7/29.7/43.8/21.9

  1. A-AD asthmatics with other coexisting atopic diseases; NA non-asthmatics; NA-NAD non-asthmatics without atopic diseases; NA-AD non-asthmatics with other atopic diseases.
  2. aSignificantly different (p-value < 0.05) from asthmatics with coexisting other atopic diseases (A-AD).
  3. bSignificantly different (p-value < 0.05) from non-asthmatics (NA).
  4. cSignificantly different (p-value < 0.05) from non-asthmatics with other atopic diseases (NA-AD).
  5. dSignificantly different (p-value < 0.05) from non-asthmatic without atopic diseases (NA-NAD).
  6. †One woman was not included in any of the four categories for being asthmatic without other atopic diseases.
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