Figure 3
From: Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors
CTC and CHC stem cell antigen expression in breast cancer patients. (A) Flow cytometric analysis of peripheral blood from 27 untreated patients across breast cancer subtypes. Box whisker plot of CHCs (EpCAM+/CD45+; red) and CTCs (EpCAM+/CD45−; gray). CHCs levels are higher than CTCs at significant levels (p < 0.0001). (B) Depiction of percentages of CHC (red scale) and CTCs (gray scale) with stem cell identify (i.e. CD44+/CD24lo).
