Figure 4 | Scientific Reports

Figure 4

From: Potent antitumor activity of a glutamyltransferase-derived peptide via an activation of oncosis pathway

Figure 4

VI-17 was significantly accumulated in hepatoma tumor and exhibited anti-tumor activity in vivo and in vitro. (A) NIR-II fluorescence for tumor-bearing nude mice at indicating time points (left) and analysis of average radiant efficiency (right), NIR-II fluorescence for isolated tumor and organs (including heart, liver, spleen, lung, kidney and stomach). (B) Tumor volume evolution in tumor-bearing nude mice during the treatment period. (C) Analysis of tumor size in VI-17 treated tumor-bearing nude mice at 30 days. (D) HE staining for hemorrhagic necrosis area of C. Data are expressed as Mean ± SD from each group. *p < 0.05.

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