Figure 5

Example images of optical stretched breast cancer cells (MCF-7). The images in top row show untreated (a) and pyrichalasin H treated cells (c) at incident laser power (P) of 140 mW from each fiber. The bottom row shows untreated (b) and treated (d) cells at P = 500 mW from each fiber. The treated MCF-7 cells show larger deformation at higher incident laser power. Scale bar is 10 μm. (e) Comparison of the deformability of untreated and treated MCF-7 cells with pyrichalasin H over time (n=5 cells). Error bars indicate \(\pm 1\) standard error of the mean. The shaded area indicates when P is increased to 500 mW. High laser power (P = 500 mW) is applied for a fixed duration of 7 seconds. Afterwards, laser power is decreased to 140 mW. (f) Summary of the deformability for individual optically stretched cell. The average deformability is marked with a magenta circle (n=10 cells). Error bars correspond to \(\pm 1\) standard deviation.