Figure 5 | Scientific Reports

Figure 5

From: Three-dimensional virtual histology in unprocessed resected tissues with photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT)

Figure 5

PARS histological imaging of nuclear morphology in unprocessed excised tumor tissues. (a) (i) Large field of view PARS image of resected Rattus mammary tumor. The inset in the upper right indicates the region of the bulk tissue section in which the PARS images were captured. Scale Bar: 1 mm. (ii, iii) Subsections of the large field of view image in (i) highlighting regions of interest within the large field images. (ii) Scale Bar: 500 µm. (iii) Scale Bar: 25 µm. (b–d) PARS histological imaging of nuclear morphology in unprocessed formalin fixed excised post-menopausal human breast tissues. The inset in the upper right highlights the region of the breast tissue section which the PARS images were captured in. (b) Scale Bar: 275 µm (c) Scale Bar: 150 µm (d) Scale Bar: 150 µm.

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