Figure 4

Prorenin receptor is increased in medullary tissues of diabetic rats. (A) PRR mRNA levels were augmented in the renal medulla in STZ rats. No differences were found in the cortex. (B) Representative immunoblot showing the induction of PRR protein levels in STZ rats as compared to controls. (C) No differences were observed in the renal cortex (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001.