Table 1 Physiological parameters of STZ rats on Day 7, body weight, blood glucose, plasma insulin, urine volume, urine protein concentration, urinary creatinine, urine protein/creatinine ratio.

From: High glucose induces trafficking of prorenin receptor and stimulates profibrotic factors in the collecting duct

 

Control (n = 7)

STZ (n = 9)

Body weight (g)

506.9 ± 11.0

426.9 ± 16.7**

Blood glucose (mg/dL)

137.7 ± 9.3

427.7 ± 12.9***

Plasma insulin (ng/mL)

2.42 ± 0.6

0.05 ± 0.02***

Urine volume (mL/24 h)

20.6 ± 1.5

106.2 ± 17.5***

Urine protein (mg/dL)

73.8 ± 4.6

203.7 ± 9,7*

Urinary creatinine (mg/dL)

Urine protein/creatinine ratio

124.2 ± 15.3

0.59 ± 0.01

31.7 ± 5.3***

6.42 ± 0.23

  1. Mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.00.
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