Figure 3

Correlation coefficient between total support and closeness, hierarchical closeness. Blue columns indicate the results on 17 cancer signaling networks and the red represents those on 100 random directed networks generated with |V| = 50 and 49 ≤ |E|≤ 100. Dark red represents the value of hierarchical closeness (R = 0.866; P = 0.0001) whereas light red is the value of closeness (R = 0.866; P = 0.0001) (see Table S1 for details).